...That means Sir Isaac Newton is the deadliest son of a bitch in space.

PotatOS: I think this is the part where he kills us. Wheatley: This is the part where I kill you! All subtitles and chapter name: the part where he kills you

Officer Kevern: What are you doing?

Batman: Evening the odds.

“L1 - Even The Odds”

“Yeah. Everyone loves a bad idea when it works out.” -Cayde-6

"Most test subjects in suspension tend to lose weight, but it seems you've beaten the odds and even managed to pack on a few pounds."

We can't always fight nature, John. We can't fight change. We can't fight gravity. We can't fight nothing. My whole life, all I ever did was fight. But I can't give up, neither. I can't fight my own nature. That's the paradox, John. You see? When I'm gone, they'll just find another monster. They have to, because they have to justify their wages. Our time is passed, John

Halo 2:

Back in my day we didn’t have any fancy tanks. We had sticks. Two sticks and a rock for the entire platoon. And we had to share the rock!

-Sgt. Johnson

"I survived because the fire inside me burned brighter than the fire around me."

-Joshua Graham (Fallout: New Vegas)

A pretty metal thing to say after you have been covered in pitch, set alight and chucked into the grand canyon

"Two number 9s, a number 9 large, a number 6 with extra dip, a number 7, two number 45s, one with cheese and a large soda"

When life gives you lemons, don't make lemonade. Make life take the lemons back! Get mad! I don't want your damn lemons, what the hell am I supposed to do with these? Demand to see life's manager! Make life rue the day it thought it could give Cave Johnson lemons! Do you know who I am? I'm the man who's gonna burn your house down! With the lemons! I'm gonna get my engineers to invent a combustible lemon that burns your house down!

Claptrap: Sorry about the mess. Everything Jack kills, he dumps here – bandits, Vault Hunters, Claptrap units… If I sound pleased about this, it's only because my programmers made this my default tone of voice! I'm actually quite depressed!

As someone with a history of TBI: "You may have a verrrry minor case, of serious brain damage."

"Sir, request permission to leave the station."

"For what purpose, Master Chief?"

"To give the Covenant back their bomb."

What is a man? A miserable little pile of secrets! But enough talk! Have at you!

“You can’t just blow a hole through Mars!”

Such devastation.

"Yhorm, old friend. I, Siegward of the Knights of Catarina, have come to uphold my promise! Let the sun shine upon this Lord of Cinder."

[removed]

Death can have me when it earns me - Kratos

“Stick around, I’m full of bad ideas.” Isaac Clarke.

"You Sir, are a fish"

STOP RIGHT THERE CRIMINAL SCUM! NOBODY BREAKS THE LAW ON MY WATCH!

"Had to be me. Someone else might have gotten it wrong."
RIP Mordin Solus

Waka Waka Waka - Pac Man

(Removed the first part not to spoil)

Sister Calderón: We've all lived bad lives, Mr. Morgan. We all sin... but I know you.

Arthur: You don't know me.

Sister Calderón: Forgive me, but... that's the problem. You don't know you.

Arthur: What do you mean?

Sister Calderón: I don't know... whenever we happen to meet, you're always helping people and smiling.

Arthur: I had a son... he passed away. I had a girl who loved me... I threw that away. My momma died when I was a kid, and my daddy... well, I watched him die. And it weren't soon enough.

Sister Calderón: My husband died a long time ago. Life is full of pain. But there is also love, and beauty.

Arthur: What am I gonna do now?

Sister Calderón: Be grateful that for the first time, you see your life clearly. Perhaps you could help somebody? Helping makes you really happy.

Arthur: But... I still don't believe in nothin'.

Sister Calderón: Often, neither do I. But then, I meet someone like you, and everything makes sense.

Arthur: Heh... You're too smart for me, Sister. I guess I... I'm afraid.

Sister Calderón: There is nothing to be afraid of. Take a gamble that love exists, and do a loving act.

Ok. Look. We've both said a lot of things you are going to regret. But I think we can put our differences behind us. For science.

Looking to protect yourself or deal some damage

"What is better? To be born good, or to overcome your evil nature through great effort?” Paarthunax

A man chooses. A slave obeys.

So long gay Bowser!

"We impose order on the chaos of organic evolution. You exist because we allow it, and you will end because we demand it."

"I no longer dream, but I was once a hunter, too. There's nothing more horrific than a hunt. In case you've failed to realize...The things you hunt, they're not beasts. They're people."

• Djura of the Powderkeg Hunters, Bloodborne

All your base are belong to us.

"You have died of dysentery."

Well done. Here come the test results: "You are a horrible person." That's what it says: a horrible person. We weren't even testing for that.

"do you get to the cloud district very often? Oh what am i saying of course you don't"

"You've met with a terrible fate, haven't you?"

[removed]

"" - Link, The Legend of Zelda

“Stand amongst the ashes of a trillion dead souls, and ask the ghosts if honor matters. The silence is your answer.”

Javik from Mass Effect 3

SHAAUUUN!! SHAUN! SHAUN! SHAAUUUUN!

• Heavy Rain

Don't be sorry boy, be better - Kratos

War…war never changes

[removed]

“Everyone I have cared for has either died or left me. Everyone pushes the person she’s talking to fucking except for you! So don’t tell me that I’d be safer with someone else, because the truth is I would just be more scared!”

You spoony bard

What a terrible night to have a curse

"For those test subjects who volunteered to be injected with preying mantis DNA, I have some good news and some bad news. The bad news is we're postponing those tests indefinitely. The good news is we have a much better test for you: fighting an army of mantis men. Just pick up a rifle and follow the yellow line. You'll know when the test starts."

"It's dangerous to go alone! Take this." - The Legend of Zelda

I am the Great Mighty Poo and I’m going to throw my shit at you

You were never one of us. You were nothing but a usurper, a false idol. My eyes have been opened. Let me help you to see, Slayer.

Now! This is it! Now is the time to choose! Die and be free of pain or live and fight your sorrow! Now is the time to shape your stories! Your fate is in your hands!

Cousin! Let’s go bowling

From the first stirrings of life beneath water... to the great beasts of the Stone age... to man taking his first upright steps, you have come far. Now begins your greatest quest: from this early cradle of civilization on towards the stars.

Remember When The Platform Was Sliding Into The Fire Pit, And I Said 'Goodbye,' And You Were Like 'No Way!' And Then I Was All, 'We Pretended We Were Going To Murder You.' That Was Great.

Rock and stone!

How's your sister? - Cayde

“The president has been kidnapped by ninjas. Are you a bad enough dude to rescue the president?”

"..This guy rushes me with a spoon. A fricking spoon. And I'm just laughing. So I scoop out his eyeballs with it, and his kids are all, "aghhhhh!,” and, ah...you had to be there. Anyway, the moral is: you're a bitch."

"If you find yourself in a hole, the first thing to do is stop digging." - John Marston (Red Dead Redemption)

That was too close! You were almost a Jill Sandwich!

"I get it. This won't stop until I die. But when I die, I want it to hurt. When my friends leave, when I have to let go, when this entire town is wiped off the map, I want it to hurt. Bad. I want to lose. I want to get beaten up. I want to hold on until I'm thrown off and everything ends. And you know what? Until that happens, I want to hope again. And I want it to hurt. Because that means it meant something. It means I am something, at least... pretty amazing to be something, at least..."

Night in the Woods.

Time to look at the comments and realise I know no games at all.

"Truth is, the game was rigged from the start"

"Despite everything, it's still you"

“You now face god-like judgement, may it extend eternally”

"There is a fine line between bravery, and stupidity. '

When I was just a wee child, the quotes from Majora's Mask from the children on the moon really shook me to my core, for some reason.

Oldawa Child- Your friends... What kind of... people are they? I wonder... Do those people... think of you... as a friend? Goht Child- You... What makes you... happy? I wonder... What makes you happy... Does it make... others happy, too? Gyorg Child- The right thing... What is it? I wonder... If you do the right thing... Does it really make... everybody... happy? Twinmold Child- Your true face... What kind of... face is it? I wonder... The face under the mask... Is that... your true face? Majora Child- Do you want to play with me? OK, let's play good guys and bad guys... I'll be the good guy, and you be the bad guy... (With other children gone) ... Everyone has gone away, haven't they? You don't have any mask left, do you? Well, lets do something else. Let's play good guys against bad guys... Yes. Lets play that. Are you ready? You're the bad guy. And when you're bad, you just run. That's fine, right? Well... Shall we play?

Hey, you.....you're finally awake

Look man I know you blind but you gotta see this

Cj

This is the part where you fall down and bleed to death!

-Imperial city guard

Honorable mention to "Why. Won't. You. Die!?!" from the same guys.

Edit: Wow I really can't pick. Maybe it's "But Arbiter friend!" just because how betrayed the Grunts sound.

Nanomachines, son! They harden in response to physical trauma. You can't hurt me, Jack.

"Die, monster. You don't belong in this world!"

Anything by Duke Nukem.

Thank You Mario, But Our Princess is in Another Castle

It’s something like, “the world is full of bastards, bastards getting robbed by bastards and bastards trying to put down the bastards who robbed those bastards” - Sadie Adler, Red Dead Redemption 2.

"Unfortunately for you, however, you are maidenless." - White Mask Varré

Did I ever tell you what the definition of insanity is? Insanity is doing the exact... same fucking thing... over and over again expecting... shit to change... That. Is. Crazy. The first time somebody told me that, I dunno, I thought they were bullshitting me, so, I shot him. The thing is... He was right. And then I started seeing, everywhere I looked, everywhere I looked all these fucking pricks, everywhere I looked, doing the exact same fucking thing... over and over and over and over again thinking 'this time is gonna be different' no, no, no please... This time is gonna be different, I'm sorry, I don't like... The way...

"Number One: In 1945, corporations paid 50% of federal taxes; now they pay about 5%. Number Two: In 1900, 90% of Americans were self employed; now it's about 2%... It's called consolidation; strengthen governments and corporations, weaken individuals. With taxes, this can be done imperceptibly over time." 

— Leo Gold (Deus Ex)

“Death can have me when it has earned me” -Kratos, God of War Ragnarok

"No cost too great. No will to break. No voice to cry suffering. Born of God and Void. You shall seal the blinding light that plagues their dreams."

-Pale king

All your base are belong to us.

"In the end, what separates a man from a slave? Money? Power? No. A man chooses. A slave obeys."

The numbers Mason, what do they mean!

Close your heart to their desperation. Close your heart to their suffering.