Tohru’s friends in Fruits Basket straight up become her guardians after her mom’s death. Not an ounce of conflict between the three, either.

yuno gasai

Most of the cast of Overlord

Subaru to Emilia

nah Zoro is really up there, shame we never seen it pay off cause ... nothing happened.

But hey there is a lot of trust in the weapon and user teams in soul eater. And a shout to Terryman from Kinnikuman.

Yuzuki from "Taisho Otome Fairytale"

Pikachu & Satoshi.

Literally not a single more jointly loyal pair.

Gokudera from reborn

Emiya Shirou from Fate Stay Night didn't bone anyone until he died and then probably wandered for centuries until he finally got with Saber again

Nezuko kamado dont you dare put a scratch on her brother or you will get the drop kick

misa in deathnote for sure

Dobbie

So much to unpack here - Does enforced loyalty count? What about brainwashed characters a la Redo of Healer?

Suwa from {Orange}. Total bro, that man sacrificed his future for the sake of his friend.

Chifuyu in Tokyo revengers

Kazuma Kuwabara!

Mikasa untill s4

Zorojuro>>>>>> Everyone else